Copper 29 Cu 63.546

Cupric Sulfate Pentahydrate USP/EP Low HM Crystals

Jost Code: 2302

Synonyms: Blue Vitriol, Copper(II) sulfate pentahydrate, Sulfuric acid, copper(II) salt (1:1) pentahydrate

Cupric Sulfate can be used as a dietary supplement and as a nutrient. Copper aids in the absorption of iron, in the formation of red blood cells and the proper bone formation and maintenance. Product specifications, SDSs and certifications are available under Additional Information.

Chemical Formula
CuSO4 · 5 H2O
CAS Number
7758-99-8
Molecular Weight
249.69
Use
Nutrient; dietary supplement
Description
Blue crystals
Containers
25 kg. / 55 lb. Fiber drums; 25 kilogram packs EU only
Storage
Store in a clean, dry warehouse in the original unopened containers.
Revision Date
07/25/2017
Assay (USP)
98.5-100.5%
Assay (EP)
99.0-101.0%
Appearance of Solution
Clear Solution S
LOD (USP)
33.0 – 36.5%
LOD (EP)
35.0 - 36.5%
Lead (Pb)
1 ppm maximum
Cadmium (Cd)
1 ppm maximum
Arsenic (As)
1 ppm maximum
Mercury (Hg)
0.1 ppm maximum
Chlorides
100.0 ppm maximum
Sodium
0.02% maximum
Potassium
0.01% maximum
Calcium
0.005% maximum
Iron
0.003% maximum
Nickel
0.005% maximum
Identification
Copper
Positive
Sulfate
Positive
Residual Solvents
Conforms to USP
Microbial Test Results
Aerobic Plate Count
1000 cfu / gram maximum
Yeast and Mold Count
100 cfu / gram maximum
Total Coliforms
Negative
Copper Content
25.0 - 25.6%
Technical Information
Related Articles
  • Frontiers in Bioscience. 2004 Sep Copper storage diseases: Menkes, Wilsons, and cancer

    The trace element copper is vital to the healthy functioning of organisms. Copper is used in a multitude of cellular activities including respiration, angiogenesis, and immune responses. Like other metals, copper homeostasis is a tightly regulated process. Copper is transported from dietary intake through the serum and into cells via a variety of transporters. There… Read Abstract

  • Survey of Ophthalmology. 2013 Nov Iron, zinc, and copper in retinal physiology and disease.

    The essential trace metals iron, zinc, and copper play important roles both in retinal physiology and disease. They are involved in various retinal functions such as phototransduction, the visual cycle, and the process of neurotransmission, being tightly bound to proteins and other molecules to regulate their structure and/or function or as unbound free metal ions.… Read Abstract

  • Nature. 2014 May Copper is required for oncogenic BRAF signalling and tumorigenesis.

    The BRAF kinase is mutated, typically Val 600→Glu (V600E), to induce an active oncogenic state in a large fraction of melanomas, thyroid cancers, hairy cell leukaemias and, to a smaller extent, a wide spectrum of other cancers. BRAF(V600E) phosphorylates and activates the MEK1 and MEK2 kinases, which in turn phosphorylate and activate the ERK1 and… Read Abstract

  • Oncotarget. 2016 Jun Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution.

    Copper-ionophores that elevate intracellular bioavailable copper display significant therapeutic utility against prostate cancer cells in vitro and in TRAMP (Transgenic Adenocarcinoma of Mouse Prostate) mice. However, the pharmacological basis for their anticancer activity remains unclear, despite impending clinical trails. Herein we show that intracellular copper levels in prostate cancer, evaluated in vitro and across disease… Read Abstract