Zinc Acetate Dihydrate USP/FCC Granular

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• J Colloid Interface. 2004 Apr Growth of layered basic zinc acetate in methanolic solutions and its pyrolytic transformation into porous zinc oxide films

  Layered basic zinc acetate (LBZA), Zn(5)(OH)(8)(CH(3)COO)(2).2H(2)O, was deposited on glass substrates by a chemical bath deposition (CBD) method using methanolic solutions of zinc acetate dihydrate. The substrates were put into bottles filled with the solutions and sealed up and were kept at 60 degrees C in a drying oven. Immersion time necessary for the deposition… Read Abstract

• J Exp Clin Cancer Res.. 2019 Jun Direct intra-tumoral injection of zinc-acetate halts tumor growth in a xenograft model of prostate cancer.

  Intracellular levels of zinc have shown a strong inverse correlation to growth and malignancy of prostate cancer. To date, studies of zinc supplementation in prostate cancer have been equivocal and have not accounted for bioavailability of zinc. Therefore, we hypothesized that direct intra-tumoral injection of zinc could impact prostate cancer growth. In this study, we… Read Abstract

• Acta Med Okayama. . 2018 Oct Effect of Zinc Acetate Dihydrate (NobelzinR) Treatment on Anemia and Taste Disorders in Patients with Chronic Kidney Disease with Hypozincemia

  Some patients with chronic kidney disease (CKD) receiving hemodialysis develop erythropoietin-resistant anemia, possibly due to zinc deficiency. The frequency of zinc deficiency in CKD (stages 1-5 and 5D) and CKD improvement via zinc supplementation are not completely verified. Here 500 CKD patients (Stage 1/2, n=100; Stage 3, n=100; Stage 4, n=100, Stage n=5, 100; Stage… Read Abstract

• Br J Clin Pharmacol.. 2016 Nov Zinc acetate lozenges for treating the common cold: an individual patient data meta-analysis.

  AIMS: The aim of this study was to determine whether the allergy status and other characteristics of common cold patients modify the effects of zinc acetate lozenges. METHODS: We had available individual patient data for three randomized placebo-controlled trials in which zinc acetate lozenges were administered to common cold patients. We used both one stage… Read Abstract

• J Org Chem. . 2017 Jul Zinc Acetate-Promoted Buchwald-Hartwig Couplings of Heteroaromatic Amines

  Zinc salts have been shown to promote the Buchwald-Hartwig coupling of azaindoles and azaindazoles with heteroaryl chlorides to provide the corresponding 1-aryl-1H-azaindoles and 1-aryl-1H-azaindazoles. The substrate scope and mechanistic aspects of this reaction were explored. Read Abstract

• BMC Fam Pract. . 2015 Feb The effectiveness of high dose zinc acetate lozenges on various common cold symptoms: a meta-analysis.

  BACKGROUND: A previous meta-analysis found that high dose zinc acetate lozenges reduced the duration of common colds by 42%, whereas low zinc doses had no effect. Lozenges are dissolved in the pharyngeal region, thus there might be some difference in the effect of zinc lozenges on the duration of respiratory symptoms in the pharyngeal region… Read Abstract

• Ultrason Sonochem. 2017 Mar Sonochemical zinc oxide and layered hydroxy zinc acetate synthesis in fenton-like reactions

  Zinc acetate solution is sonicated at high power in water and in ethanol in the absence and presence of various peroxides. In the absence of peroxides, the products are zinc oxide and layered hydroxy zinc acetate in water and in ethanol, respectively. Layered basic zinc acetate are prepared for the first time using sonochemical methods.… Read Abstract

• Ann Pharmacother.. 1998 Jan Zinc acetate treatment in Wilson's disease

  OBJECTIVE: To briefly review the pathophysiology and diagnosis of Wilson’s disease, and to evaluate the pharmacology, pharmacokinetics, clinical utility, adverse effects, dosing regimens, and pharmacoeconomics of zinc acetate therapy in Wilson’s disease. DATA SOURCES: A MEDLINE search (December 1966-December 1996) of the English-language literature using the terms zinc and Wilson’s disease was conducted to identify… Read Abstract

• Drug Deliv Transl Res. . 2017 Dec MIV-150 and zinc acetate combination provides potent and broad activity against HIV-1

  We previously showed that the combination of the non-nucleoside reverse transcriptase inhibitor (NNRTI) MIV-150 with zinc acetate (ZA) formulated in a carrageenan (CG; MZC) gel provided macaques significant protection against vaginal simian-human immunodeficiency virus-RT (SHIV-RT) challenge, better than either MIV-150/CG or ZA/CG. The MZC gel was shown to be safe in a phase 1 clinical… Read Abstract

• Clin Infect Dis.. 2000 Nov Effect of treatment with zinc gluconate or zinc acetate on experimental and natural colds

  Two clinical trials were conducted, one involving 273 subjects with experimental rhinovirus colds and the other involving 281 subjects with natural colds. Symptomatic volunteers were randomized to receive oral lozenges containing zinc gluconate (13.3 mg), zinc acetate (5 or 11.5 mg), or placebo. The median duration of illness in zinc gluconate recipients was 2.5 days,… Read Abstract

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