Cupric Oxide Purified Powder

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• Frontiers in Bioscience. 2004 Sep Copper storage diseases: Menkes, Wilsons, and cancer

  The trace element copper is vital to the healthy functioning of organisms. Copper is used in a multitude of cellular activities including respiration, angiogenesis, and immune responses. Like other metals, copper homeostasis is a tightly regulated process. Copper is transported from dietary intake through the serum and into cells via a variety of transporters. There… Read Abstract

• Survey of Ophthalmology. 2013 Nov Iron, zinc, and copper in retinal physiology and disease.

  The essential trace metals iron, zinc, and copper play important roles both in retinal physiology and disease. They are involved in various retinal functions such as phototransduction, the visual cycle, and the process of neurotransmission, being tightly bound to proteins and other molecules to regulate their structure and/or function or as unbound free metal ions.… Read Abstract

• Nature. 2014 May Copper is required for oncogenic BRAF signalling and tumorigenesis.

  The BRAF kinase is mutated, typically Val 600→Glu (V600E), to induce an active oncogenic state in a large fraction of melanomas, thyroid cancers, hairy cell leukaemias and, to a smaller extent, a wide spectrum of other cancers. BRAF(V600E) phosphorylates and activates the MEK1 and MEK2 kinases, which in turn phosphorylate and activate the ERK1 and… Read Abstract

• Oncotarget. 2016 Jun Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution.

  Copper-ionophores that elevate intracellular bioavailable copper display significant therapeutic utility against prostate cancer cells in vitro and in TRAMP (Transgenic Adenocarcinoma of Mouse Prostate) mice. However, the pharmacological basis for their anticancer activity remains unclear, despite impending clinical trails. Herein we show that intracellular copper levels in prostate cancer, evaluated in vitro and across disease… Read Abstract

• Waste Management & Research. 2017 Jun Optimisation of chemical oxygen demand removal from landfill leachate by sonocatalytic degradation in the presence of cupric oxide nanoparticles.

  Leachate is the liquid formed when waste breaks down in the landfill and water filters through that waste. This liquid is very toxic and can pollute the land, ground water, and water resources. In most countries, it is mandatory for landfills to be protected against leachate. In addition to all other harms to the environment,… Read Abstract

• Biosensors and Bioelectronics. 2018 Feb Efficient label-free chemiluminescent immunosensor based on dual functional cupric oxide nanorods as peroxidase mimics.

  Dual-functional cupric oxide nanorods (CuONRs) as peroxidase mimics are proposed for the development of a flow-through, label-free chemiluminescent (CL) immunosensor. Forming the basis of this cost-efficient, label-free immunoassay, CuONRs, synthesized using a simple hydrothermal method, were deposited onto epoxy-activated standard glass slides, followed by immobilization of biotinylated capture antibodies through a streptavidin bridge. The CuONRs… Read Abstract

• Scientific Reports. 2019 Feb Electromagnon excitation in cupric oxide measured by Fabry-Pérot enhanced terahertz Mueller matrix ellipsometry.

  Here we present the use of Fabry-Pérot enhanced terahertz (THz) Mueller matrix ellipsometry to measure an electromagnon excitation in monoclinic cupric oxide (CuO). As a magnetically induced ferroelectric multiferroic, CuO exhibits coupling between electric and magnetic order. This gives rise to special quasiparticle excitations at THz frequencies called electromagnons. In order to measure the electromagnons… Read Abstract

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